Upload your DNA¶
Yeliztli analyses the raw data file you can download from a consumer genotyping service.
Supported files¶
| Service | Versions | File type |
|---|---|---|
| 23andMe | v3, v4, v5 | .txt or a single-file .zip containing the raw .txt |
| AncestryDNA | v2.0 | .txt or a single-file .zip containing the raw .txt |
Yeliztli auto-detects the service and format from the file header — you don't need to tell it which one you have. (Both are genotyping-array exports on the GRCh37 build; older 23andMe v3 files on GRCh36 are lifted over automatically.)
Where to get your raw data
Each service has its own "download raw data" option in your account settings. Yeliztli needs that raw file — not the polished reports the service shows you on its website.
Both services download your raw data inside a .zip by default. Yeliztli accepts that archive when it contains exactly one raw .txt file; extract the .txt first if your archive contains anything else.
How to upload¶
- Click Upload from the dashboard or sidebar.
- Drag and drop your file (or click to browse).
- Yeliztli parses the file and shows progress.
- Annotation runs automatically in the background, followed by the analysis modules.
- You're taken to the dashboard while annotation runs. Watch the Annotation Pipeline panel there for progress, ETA, and the Cancel annotation control; after a terminal status is dismissed, the panel also offers Run Annotation for re-runs. A standard file (~600,000 markers) typically finishes in a couple of minutes after the one-time reference-data setup has already completed.
That timing estimate is for per-sample annotation only. First-run reference-data setup is a separate, much longer download/build step; see reference data.
If annotation is interrupted, Yeliztli simply re-runs it from scratch (it's fast enough that no checkpointing is needed).
More than one file?¶
If you've tested with more than one service, you can upload additional files and group files from the same person under a single individual — and optionally combine them into one merged sample with a concordance check. Each uploaded sample otherwise keeps its own isolated database; use the sample selector in the top navigation to switch between them. See multi-sample merging for the full walkthrough.
Next: read your results.